Oh man, that’s like asking what kind of wine to drink with one’s meal. Super depends on the kind of tones/flavors you like.
I know most people actually have a handful of different koma that they have acquired over the years to experiment with what kind of sounds they can achieve. And placement is even key in produce one’s favorite tone. That aside, having a spare koma is never a bad idea xP
But you do ask a really good question; what tones sound “best”, or “better” with a synthetic skin?